Diagnostic Reading #25: Five “Must Read” Articles on HIT and Radiology

“Dirty data” and precision medicine make news

patient holding DRX digital radiography X-ray detector over one knee

This week’s articles include: dirty data wanted for research; a blockchain distributed database might be viable for management of decentralized data; a three-modality molecular imaging system can detect certain types of atherosclerotic plaque that are more prone to rupture; technology leaders rate the state of precision medicine as a three on a scale of one to 10; and a new NIH precision medicine program wants 1 million plus participants to donate data as part of a genomics initiative.

Wanted: more data, the dirtier the better – Scientific American

Purvesh Khatri, a computational immunologist at Stanford University, has adopted a new approach to genomic discovery that calls for scouring public repositories for data collected at different hospitals on different populations with different methods. If a signal sticks around despite the heterogeneity of the samples, you can bet you’ve actually found something, according to Khatri.  

Will healthcare IT go blockchain? – Health IT Central HIMSS Europe

The potential of blockchain as a viable proposition for the management of decentralized healthcare data is rapidly gaining momentum. In simple terms, blockchain is a distributed database for recording and storing transaction records among groups of peers who share the responsibility for authorizing and validating each transaction. Essentially, it is a cloud-based transaction ledger in which transactions are time-stamped and signed using private encryption keys.

SNMMI: PET can detect which plaques are at risk of rupture – Auntminnie

A three-modality molecular imaging system that combines PET with photoacoustic imaging can detect which plaques might rupture and induce a major adverse cardiac event, according to research presented at the Society of Nuclear Medicine and Molecular Imaging (SNMMI) annual meeting. Researchers have understood for some time that certain types of atherosclerotic plaque including thin-cap fibroatheromas are more prone to rupture, leading to embolism and possibly death.

Widespread precision medicine is still years away, experts say – Healthcare IT News

While the industry is rapidly making progress on precision medicine, cultural, policy and regulatory changes are limiting momentum, according to industry leaders at the Precision Medicine Summit. When pressed on the current state of the innovative technology, technology leaders say that the industry is still years away from full utilization. In fact, on a scale of one to 10, most would place precision medicine at a three in terms of progress.

NIH precision medicine program wants a million-strong cohort, from all walks of life – Healthcare IT News

Eric Dishman, director of the All of Us Research Program, explains the goals of the landmark genomics initiative. His goal is to collect data from more than 1 million individuals and use whole-genome sequencing to develop individualized treatment. He wants to include greater numbers of women and ethnic minorities, who have been under-represented in past forms of research.

Check back next Friday for a new issue of Diagnostic Reading. #healthIT #radiology #diagnosticreading

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