In-Vivo FX PRO
The In-Vivo FX PRO elevates sensitivity, throughput and ease of use to an entirely new level. The system combines high-sensitivity optical molecular imaging and high resolution digital x-ray to deliver precise anatomical localization of molecular and cellular biomarkers in vivo. New full precision automation simplifies complex multimodal imaging protocols for small animal imaging. The In-Vivo FX PRO also protects your investment with a seamless upgrade path to multispectral imaging capabilities.
- Greatly enhances anatomical localization of molecular discovery agents in small animals, bones, organs and tissues
- Allows precise, longitudinal study of biological processes at the cellular and tissue level in basic research, drug discovery, drug development and therapeutic monitoring applications in small animals
- Precision automation enables switching between modalities simply through customized protocols, all without moving the subject.
- Image capture control software allows complex imaging protocols to be established, stored and repeated with little or no manual manipulation.
- Rapid multimodal imaging using our powerful new broad spectrum 400W Xenon illumination source
- Large imaging area suitable for imaging 5 mice simultaneously in all modalities
- Seamless upgrade path to multispectral imaging and unmixing capabilities
- A complete system, with everything you need to perform small animal imaging and subsequent image analysis.
The In-Vivo FX PRO is a powerful, versatile solution designed for high throughput small animal imaging in basic research, drug or biopharmaceutical development, and probe and biomarker validation.
Applications include:
- Oncology
- Neuroscience
- Cardiology
- Bone disease
- Metabolic disease
- Autoimmune disorders
- Infectious disease
- Inflammation
and more.
- 4 megapixel digital CCD camera, cooled to -29C abs.
- High precision, 10X zoom lens enables automatic focusing and precise repositioning of settings for repeatable results.
- Automated excitation and emission filter systems with 15 excitation filter positions and 4 patented wide angle emission filter positions deliver outstanding fluorescent imaging sensitivity and flexibility.
- Automated 5-position x-ray filter system allows multiple energy measurements for enhanced bone density and enhanced imaging of soft tissue structures.
- Radiographic and radioisotopic imaging screens
- Automated animal heater unit
- Optional Multimodal Animal Rotation System (MARS) for 360 degree coverage of your subject.
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Camera
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CCD
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CCD-2048 x 2048 pixels
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Cooling
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-29°C absolute
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Lens
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Computer Controlled 10X zoom, 20 - 200mm, ƒ2.5
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Illumination
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Fluorescence
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Automated 15-position selectable multiwavelength epi-illumination, 410 - 760 nm – includes 14 excitation filters and new powerful 400 W Xenon illumination source
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White Light
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White light epi-illumination and white light transillumination
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Emission Filters
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Automated selectable wide angle filters, 535 - 830 nm - includes 6 emission filters
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Performance
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Field of View
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2 x 2 cm to 20 x 20 cm, continuous automated zoom
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Optical Resolution
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(max.) 10 micron/pixel
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Data Acquisition
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16-bit single capture
n-bit data acquisition
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Binning
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1x2, 2x2, 1x4, 2x4, 4x4, 1x8, 2x8, 4x8, 8x8, 16x16
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| Dark Current |
<= 5x10-5 e/Pixel/Sec |
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Read Noise
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<7 e rms (Nominal)
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Dynamic Range
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>4 OD
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Quantum Efficiency
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@ 470nm > 55%
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Detection Modes
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Multiwavelength Fluorescence
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Luminescence
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Radioisotopic
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X-ray
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Exposure Modes
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Single Capture
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Multiple Capture
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Progressive Exposure
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Time Lapse Exposure
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Computer
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Ethernet
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Operating Systems
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WINDOWS XP / MACINTOSH OS X
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Digital X-ray
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Energy Range
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Approximately 12-35 kVP
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Resolution Contact
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>= 25 lp/mm (nominal)
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Maximum Current
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Approximately 150uA
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Spot Size
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<50 U
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Target Material
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Tungsten
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Window Filtration
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Beryllium
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Cone of Illumination
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>33 degrees
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Field of Illumination
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20 X 20 cm
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Instrument
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Approximate Dimensions (in)
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(in) 41 x 19 x 38; (cm) 104 x 48 x 97 (l x w x h)
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Approximate Net Weight
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313 lbs
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